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Human Mn-SOD gene transgenic mice show reduced severity of free radical-induced pulmonary damage and adriamycin-induced myocardial damage

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[DOI] [PMC free article] [PubMed] [Google Scholar] 183.Guerrero-Ferreira R., Taylor N.M., Arteni A.A., Kumari P., Mona D., Ringler P., Britschgi M., Lauer M.E., Makky A., Verasdonck J., et al

Winter J, Ilbert M, Graf PCF, Ozcelik D, Jakob U (2008) Bleach activates a redox-regulated chaperone by oxidative protein unfolding

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The presence of a disulfide bridge, combined with the addition of tyrosine at the N-terminus, significantly enhances the peptides stability, making it orally active [8]
