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Organizing action of prenatally administered testosterone propionate on the tissues mediating mating behavior in the female Guinea pig

bioRxiv (Cold Spring Harbor Laboratory) 2023

Abstracts Cuglievan B , Jen WY, Short NJ, Bataller A, DiNardo CD, Loghavi S, Daver N, MD, Farhat A, Hajjar GE, McCall D, Gibson A, Garcia M, Nunez C, Roth M, Kadia TM, Bazinet A, Jabbour E, Montalban-Bravo G, Ravandi F, Garcia-Manero G, Andreeff M , Kantarjian HM, Issa GC

Yes, older adults and those with other health problems might need different doses

Although clinical and laboratory improvement can be seen with steroids, hepatic sarcoid can eventually progress to cause portal hypertension, bile duct depletion, and fibrotic changes, at which point steroids are unlikely to be of benefit