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In summary, mitochondrial OCM primarily uses serine as a one-carbon source and plays a critical role in supporting biosynthetic processes such as nucleotide synthesis, protein synthesis and methylation, particularly under conditions of high proliferative demand and cellular stress [17]

GSN/GSF, Glutamate synthase

21,22 When amino acids are ingested by the human body from food, in addition to being used for protein and other biomolecular synthesis, they can also be oxidized to urea and carbon dioxide as energy sources through oxidative pathways

Diagnostic Pathology

Wang S, Sun X, Yuan Q (2018) Strategies for enhancing microbial tolerance to inhibitors for biofuel production: a review

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