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Bartels GL, Remme WJ, Holwerda KJ, Kruijssen DA

Plasma samples were collected from mice after a 12-h fasting period

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Blocking mitochondrial lactate/pyruvate uptake through MCT1, rather than MCT4, is anticipated to inhibit lactate utilization, leading to cytotoxic effects due to enhanced glycolysis and impaired mitochondrial respiration [104]

PloS One (2017) 12:e0189310