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Intramuscular (IM) injection is the most invasive and costly administration method, requiring trained personnel and clinical visits

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TB4 has demonstrated a key role in general cellular function and modulation of the immune system

Whether performed via laparoscopy or robotic surgery , these techniques allow for the precise removal of the fibroid while minimizing trauma to the rest of the body

Tumors derived growth factors like TGF- and platelet-derived growth factor (PDGF) activates the fibroblasts present within the CAFs, which in turn release abundant ECM proteins, leading to desmoplasia with abundant collagen I/III, fibronectin, and other fibrillar matrices (110)