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Here we review the current advances in therapeutic efforts for PD that aim to produce a disease-modifying therapy by targeting the spread, production, aggregation, and degradation of alpha-synuclein

doi: 10.1093/eurjpc/zwab001 28 DelucchiFBerniRFratiCCavalliSGraianiGSalaRet al

Ferroptosis can be experimentally induced by direct inhibition of Gpx4 via Ras-selective lethal small molecule 3 (RSL3) or by genetic knockdown or deletion of Gpx4 (Yang et al., 2014)

B., Hilal, Z., Kern, P., Juhasz-Boess, I
Overcoming these limitations has become a key challenge in medicinal chemistry

GLP-1 Agonists for Metabolic Reset When appropriate, we use GLP-1 medications (semaglutide, tirzepatide) as part of comprehensive metabolic support
