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It activates phase 2 enzymes by signaling through nuclear factor erythroid 2related factor 2 (Nrf-2) and interacting with the Keap1 protein
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Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions
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For individuals with deeper pigmentation or melasma, fractional lasers provide a more intensive melanin reduction treatment option for hyperpigmentation
