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Research has demonstrated that EGCG shields the heart muscle from ischemia-reperfusion damage by increasing the levels of 14-3-3 protein, which subsequently inhibits autophagy and ferroptosis ( Despite some progress, studies focusing on autophagy-related signaling and protein degradation pathways in MIRI remain scarce

This Study was supported by following grants: Science & Technology Department of Sichuan Province (grant numbers 2022ZYD0086,2023NSFSC0616), Clinical Science Research Fund of The Second Affiliated Hospital of Chengdu Medical College, China Nation Nuclear Corporation 416 Hospital (grant number23LHHGYMP06)

doi: 10.1002/hep.20035

[1] Unlike many nutrients, B12 is well-stored in the liver, with body reserves typically lasting several years

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[7]Reeves, Benjamin D