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Notably, post-mortem studies revealed reduced activity of respiratory chain complexes in a group of ASD children, suggesting that abnormalities, especially in the frontal, temporal and cerebellar areas (Chauhan et al., 2011

SAS/STAT Users Guide, 2009

Patients experiencing significant gastrointestinal side effects may benefit from temporary dose reduction or slowing the titration schedule

When pain management is not achieved, a person should be referred to a neurologist or pain specialist

L-carnitine and the aging process It is believed that the decrease in the mitochondrial function contributes to the aging process

Given the numerous potential secondary causes, the PIANIST mnemonic (Psychiatric, Iatrogenic/Intoxicant, Anemia, Nutrients, Infection, Sleep, Thyroid/hormonal) can be used to aid in identification (Table 1)