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Targeted metabolomics analysis revealed that GGCT knockdown significantly reduced the abundance of TCA cycle intermediates, while GGCT overexpression substantially increased their levels

Curcumin, a bioactive polyphenol sourced from Curcuma longa, has gained attention as a potentially beneficial agent for enhancing cardiometabolic health

Here the authors report a phase I clinical trial assessing the safety of clinically formulated TS in mesothelioma patients, and identify SLC7A11 as a potential mediator of TS resistance in pre-clinical models.

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