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In addition, high levels of VEGF and HIF-1 are linked with resistance to therapy and metastatic progression in clinical settings

A randomized phase III trial evaluated selenium supplementation in selenium-deficient gynecological cancer patients receiving adjuvant radiotherapy, and it proved effective in reducing the incidence of grade 2 diarrhea, particularly in patients with a large planning target volume (387, 388)

Bilateral ensures left and right sides receive equal stimulation (preventing one arm growing while the other doesnt)

These selenoproteins play crucial roles in the production of thyroid hormones and in maintaining their stability in the body

, Issekutz, A

Conte M, Martucci M, Chiariello A, Franceschi C, Salvioli S