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If cloudiness persists, allow vial to rest for 5-10 minutes and gently swirl again

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Once phosphorylated and activated by PKA, hormone-sensitive lipase translocates to lipid droplets within the fat cell and begins breaking down stored triglycerides into free fatty acids and glycerol

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Instead, its activity is believed to be mediated via adipocyte-specific signaling cascades, which gives the fragment a uniquely narrow pharmacological footprint for a peptide of its molecular size and makes it attractive to investigators who want clean lipolytic readouts