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This central macrophage hub is encircled by a heterogeneous population of immune cells including neutrophils, DCs, T cells, B cells, and fibroblasts

The answer is both simple and important

Surg Clin North Am 91(4):771785
R., Jiang, H., Kalin, J

The selected particles were then subjected to reference-based motion correction in cryoSPARC (v4.5.0), followed by several rounds of heterogeneous refinement using volumes of different states of SLC33A1, resulting in a final stack of 215,071 particles
Unfortunately, the molecular mechanisms underlying the development of endometriosis remain unresolved, and the multifaceted symptomatology of the disease makes its diagnosis and management complex [3]
