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Cardiac involvement in hemochromatosis

[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Tsutsui H., Kinugawa S., Matsushima S

This patient's benign-appearing stellate cells in a loose myxoid stroma lacking malignant vascular channels make a right atrial angiosarcoma unlikely

These data, together with mechanistic work showing that insulin stimulates VEGF and IGF production while glucose primes macrophages for inflammatory cytokine release 394 , suggest that the combination of high glucose and high insulin is more deleterious than hyperglycemia alone
Mcdaniel et al., 2017)
