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RNA purity and quantification were assessed using a NanoDrop 2000 spectrophotometer (Thermo Scientific, USA)

Peer review information: Primary Handling editor: Jennifer Sargent, in collaboration with the Nature Medicine team

Frequency Primary carnitine deficiency occurs in approximately 1 in 100,000 newborns worldwide

Open trial of vitamin B12 nasal drops in adults with myalgic Encephalomyelitis/Chronic fatigue syndrome: comparison of responders and Non-Responders

Kinetic mechanism of the Escherichia coli UDPMurNAc-tripeptide D-alanyl-D-alanine-adding enzyme: use of a glutathione S-transferase fusion

It is higher than that of water (around 0.15 17 ), which does not dissolve cisplatin, and similar to that of cisplatin-dissolving DMSO (0.83 18 )