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Glutathione helps neutralize and clear arsenic out of cells before it can damage other biomolecules

CB-839, a GLS inhibitor that blocks the conversion of glutamine into glutamate, reduced the production of R-2-HG in AML cell lines and patient tissues harboring IDH1/2 mutations 123

A naturally occurring tripeptide antioxidant present in virtually every mammalian cell

577 , 8288 (2019) Zhu, S., Wang, S., Xia, M., Wang, B., Huang, Y., Zhang, D., Zhang, X., Wang, G.: Intracellular imaging of glutathione with MnO 2 Nanosheet@Ru (bpy)3 2+ UiO-66 nanocomposites

LRP: a multifunctional scavenger and signaling receptor

(111) studied Huntingtons gene-mutant mice and found that EODF slowed disease progression, increased survival rates, improved motor performance, reduced brain atrophy, and decreased huntingtin aggregate formation and caspase activation, normalized glucose regulation, and restored BDNF and chaperone protein levels in the cortex and striatum compared to the AL group