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pH Considerations : The pH of the solvent can significantly impact peptide stability

NO-releasing agents, such as JS-K ( O 2 -(2,4-dinitrophenyl)-1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate) 123 and PABA/NO ( O 2 -[2,4-dinitro-5-( N -methyl- N -4 carboxyphenylamino)phenyl] 1- N , N -dimethylamino)diazen-1-ium-1,2-diolate) 124 , are able to induce differentiation and cell death in a variety of cancer cells through GSH consumption, DNA synthesis inhibition and inhibition of enzymes involved in the defense against cell damage

Inhibition of AKT signaling by a small molecule KP372-1 induces apoptosis in AML

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trans-3,5-dimethoxy-4-hydroxystilbene) is a polyphenolic compound that is the dimethylether analog of resveratrol, with two methoxy groups that increases its oral absorption and bioavailability (Figure 9A) [205]

Penalva R, Esparza I, Larraneta E, Gonzlez-Navarro CJ, Gamazo C, Irache JM