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Over time, spinal ligaments can thicken and further reduce space within the spinal canal

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For instance, delivering genes that encode neurotrophic factors like GDNF (glial cell line-derived neurotrophic factor) could support dopaminergic neurons and slow down the progression of the disease

Instead, healthcare providers usually prescribe one medication at a time and may switch treatments if needed

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Accordingly, the regained muscle-to-bone reattachment can be linked to a particular musclebrain circuit to accommodate coordinated action on the quadriceps muscles [11,12]