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Furthermore, Acly -/- mouse embryonic fibroblasts (MEFs) are dependent on exogenous acetate for viability, suggesting that acetyl-CoA synthesis by ACSS2 is the primary compensatory mechanism in the absence of ACLY 4

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It does not act as a magic solution, but it may support a more organized health routine when combined with sleep, hydration, movement, and balanced food choices

[DOI] [PMC free article] [PubMed] [Google Scholar] 91.Ferlemi A.V., Makri O.E., Mermigki P.G., Lamari F.N., Georgakopoulos C.D