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Prebiotic (1.76 mg inulin) and synbiotic (1.76 mg inulin with 1,000 cfu of Lactobacillus lactis subsp

Copyright 2020, Jenkins et al

Lipid peroxidation, following the actions of ROS, induces membrane permeabilization in the early stages
Kong L, Li XT, Ni YN, Xiao HH, Yao YJ, Wang YY, Ju RJ, Li HY, Liu JJ, Fu M, et al

doi:10.1016/S0076-6879(05)01005-0

Readouts should triangulate source and compartment by using matrix/IMS-targeted reporters for H 2 O 2 dynamics, peroxiredoxin-3 (Prx3) redox state as a fast sentinel of matrix oxidant load and functional recovery after stress (e.g., respiration, contractility, cell survival) to confirm that interventions restore signallingdamage balance rather than merely lower bulk ROS (Cardozo et al