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[DOI] [PMC free article] [PubMed] [Google Scholar] 113.Marzilawati AR, Ngau YY, Mahadeva S

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Only 10 EDS dermatosparaxis patients have been reported, all presenting a recognizable phenotype with characteristic facial gestalt, extreme skin fragility and laxity, excessive bruising, and sometimes major complications due to visceral and vascular fragility

The ionotropic receptorsNMDA (N-methyl-D-aspartate), AMPA (-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), and kainate receptorsmediate fast, excitatory synaptic transmission by directly regulating ion flux