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However, more research is still required on Vitamin B12 supplements on cognitive function and memory

We discovered that Diphenyleneiodonium chloride (DPI), an inhibitor of flavoprotein enzymes and mitochondrial complex I, synergizes with mitoquinone mesylate (MitoQ), a mitochondria-targeted antioxidant in 2D and 3D in vitro models of NB

PubMed searches return zero combined trials as of early 2026

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Kong et al., similarly uncovered synergy between a complex I inhibitor and a mito-antioxidant in cancer cells, suggesting their ability to reduce mitochondria-derived H 2 O 2 levels as a potential mechanism of action ( 2 O 2 levels increased after 24 hours of (M+D)/2 and (M+D+V)/3 treatments