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The synthesis also reveals structural gaps in the literature

ALS models often exhibit transport failure, causing the accumulation of organelles in axons and defects linked to mutations in transport-related genes like KIF5A and ANXA11 (38)

Oxidative stress is a major hallmark of skin aging that may lead to DNA damage, mitochondrial dysfunction, and inflammation at the cellular levelall of which contribute to aging skin

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doi: 10.1093/jn/138.6.1047 171

Senolytic peptide FOXO4-DRI selectively removes senescent cells from in vitro expanded human chondrocytes
