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The medication works by enhancing insulin secretion in a glucose-dependent manner, suppressing glucagon release, and slowing gastric emptying, which collectively improves glycemic control and promotes weight loss

White CC, Viernes H, Krejsa CM, Botta D, Kavanagh TJ: Fluorescence-based microtiter plate assay for glutamate-cysteine ligase activity

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A pooled analysis of over 11,000 patients showed an adverse event profile comparable to placebo (Tuthill et al., Ann N Y Acad Sci 2010)

Although iodine deficiency was associated with goitre and thyroid nodules, PTC appears to be more common in areas with high iodine intake, which points to the complex relationship between iodine intake and thyroid disease (174)