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In general, a urine flow rate of less than 1 L per day increases the risk of stone formation (Curhan 2012), and guidelines for people with a history of kidney stones include the recommendation to maintain their urine output above 2 L per day (Antonelli 2015)

Kidney function, genetic factors, and the amount of a fat (propionate) that the gut microbiome produces, also influence MMA

Never freeze reconstituted peptides
Apply once daily rather than twice

One compound that has gained significant attention in regenerative and functional medicine is copper peptides , specifically GHK-Cu

Injecting B12 on top of an undiagnosed cause masks the underlying deficiency picture and can delay diagnosis of pernicious anaemia
