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Together with the absence of symptoms associated with IGF-1-mediated effects such as fluid retention, tissue edema, or impaired glucose tolerance, these results demonstrate that AOD-9604 does not activate the growth hormone/IGF-1 pathway and therefore functions through an entirely appetite-independent mechanism

Its role in appetite suppression is less defined

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However, results can be different for each person

She made sure I was comfortable and explained what each product was doing

Both studies adjusted for alcohol consumption as a standard covariate in multivariable models alongside age, sex, smoking, cirrhosis, and AST to isolate metabolic effects