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[DOI] [PMC free article] [PubMed] [Google Scholar] 266.Sextius P, Betts R, Benkhalifa I, Commo S, Eilstein J, Massironi M

doi: 10.1016/j.toxlet.2005.03.004

Brain 131 , 14641477 (2008)

Symptoms include: Low BMR Feeling cold Tiredness Weight gain Cushings Syndrome and Addisons Disease Cushings syndrome is caused by the overproduction of cortisol (hypercortisolism)

XueYBarkerNHoonSHePThakurTAbdeenSRet alBortezomib stabilizes and activates p53 in proliferative compartments of both normal and tumor tissues in vivo

91 Therefore, clinical studies on conservative treatment are lacking, and, likewise, the natural course is largely unknown