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Carnitine metabolism in hypertensive heart failure

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Hepatic enzyme aberrations, including ALT and AST increases, were observed due to oxidative stress during modified fasting

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Materials, Reagents, and Chemicals Qualified l-carnitine l-tartrate standard (99.37% equivalent to 67.79% l-carnitine) and crotonoylbetaine (impurity A) were kindly provided by Poursina pharmaceuticals (Tehran, Iran)

Under normal conditions, the primary source of energy in the heart is mainly oxidative phosphorylation of fatty acids in the mitochondria