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Abstract -Glutamylcysteine (-EC) can increase intracellular glutathione (GSH) levels, which may prevent and alleviate age-related disorders and chronic diseases caused by oxidative damage

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Moreover, HEK-293 cells showed increased extracellular formate and hypoxanthine levels, reflecting mitochondrial dysfunction and disruptions in purine metabolism caused by oxidative stress (Oizel et al., 2020)

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The authors suggest that their studies provide insights into A42 and brain insulin resistance as a significant contributing component of the pathophysiology of AD (180)