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10.3389/fphar.2022.898072 66 ZhangY.MiaoY.XiongX.TanJ.HanZ.ChenF.et al

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In normal individuals, IGF-1 can not only be delivered to target tissues by insulin-like growth factor binding proteins (IGFBPs) as a circulating hormone, but also synthesized in target organs, where it exerts actions through paracrine and autocrine mechanisms [8,9]

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Study Drug and Procedures Participants were required to remain at the study site from the evening of Day 1 until the morning of Day 7

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