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In contrast, GHK-Cu is generally non-irritating and safe for most skin types

Patients with previously treated late Lyme arthritis however, may have persistent swelling as a manifestation of antibiotic refractory late Lyme arthritis (now also called post-infectious Lyme arthritis), a persistent form of synovitis following antibiotic treatment (9496)

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Zhang YP, Eber A, Yuan Y, et al