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In vivo DCVC causes its primary lesion in the straight segment (S-3) of the proximal tubule, and the molecule is also cytotoxic both for primary cultures of proximal tubular cells and for cell lines derived from this region of the nephron

Bioinformatics 27:27722773

DSIP is reconstituted with bacteriostatic water and administered by subcutaneous injection, typically in the 100 to 600 mcg dose range, 30 to 60 minutes before intended sleep onset

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