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HER2-directed therapy: current treatment options for HER2-positive breast cancer

This interaction triggers the assembly of a signaling complex that includes interleukin-1 receptor-associated kinases and TNF receptor-associated factor 6, leading to the activation of nuclear factor kappa B (NF-B) and mitogen-activated protein kinases (MAPKs) such as p38 and JNK [128]

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This course counts as 10 CPD hours