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T., Pyo, J.-H

This work has been funded by the German Research Foundation (DFG) through grant LE LE2905/1-2 to LIL as part of the priority program 1710 Dynamics of Thiol-based Redox Switches in Cellular Physiology

Sensitivity of Muscle Fiber Types to Oxidative Stress Different muscle fiber types exhibit varying sensitivities to oxidative stress

By inhibiting this enzyme, A1AT decreases the production of superoxides, contributing to a reduction in the overall ROS burden in tissues and helping to limit oxidative damage ( Furthermore, A1AT binds to metal ions such as copper (Cu) and iron (Fe), which catalyze ROS production via the Haber-Weiss and Fenton reactions

Denaturation and excessive buffer exchange of GSTs, to yield completely GSH-free stocks, did not permit the study of binding capabilities based on protein structure

The MS conditions in positive mode were as follows: HV voltage: 4000 kV
