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sEVs from the epididymis, often called epididymosomes, transfer proteins and RNAs that activate key signaling pathways, such as CatSper-mediated calcium signaling [53], leading to influx of calcium that is necessary for promoting sperm motility, especially hyperactivated motility, which is vital for navigating the female reproductive tract

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Certain toxin-induced models of demyelination are initiated by the injection of toxic compounds such as lysophosphatidylcholine (LPC), lipopolysaccharide (LPS), or ethidium bromide into white matter areas to create a focal lesion at the injection site

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