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Mechanistically, EEEP - induced lipid peroxidation and MDA accumulation were blocked by the Nrf2 activator NK - 252

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To test this, mice were injected with bleomycin in trachea, followed by a single pleural injection of a Cathepsin B inhibitor Z-FA-FMK that irreversibly blocks the active center of Cathepsin B

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Which is where PASV mode comes in to play

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Stated differently, SC-Exo inherit anti-inflammation, immunomodulation, and tissue regeneration properties from their parental cell of origin

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