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The conjugating or detoxification reactions of Phase II included sulfation, glucuronidation, acetylation, methylation and amino acid conjugation that are more hydrophilic than parent compounds [135]
The cells were first cultured in the presence of different concentrations of Tim-AIII for 48 h
doi: 10.1523/JNEUROSCI.0143-10.2010
doi:10.1016/j.actbio.2023.02.018 326
320 GouLZhaoLSongWWangLLiuJZhangHet al
This lactate propensity implied the vicious circle of sepsis, where patients at their terminal stages always exhibited refractory and critical immunosuppressive effects [156, 158]
