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For example, preclinical in vivo studies performed by Boban-Blagic et al

The isolated fraction induced delta-wave (slow-wave) sleep when injected into recipient animals giving the peptide its name and initiated one of the most distinctive research trajectories in neuropeptide biology: a compound with a clearly demonstrated biological name-property, an exceptionally wide pharmacological activity profile, and nearly five decades later a receptor that remains formally uncharacterised

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Down-regulation of K(+) channels by human parvovirus B19 capsid protein VP1

It carries no amidation, no acetylation, no disulfide bonds, and no cyclization structurally simple by peptide standards

[DOI] [PubMed] [Google Scholar] 481.Groenendaal F, Lammers H, Smit D, Nikkels PG