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Mouse model of B12 deficiency Female C57BL/6 and SCID mice were fed with a diet similar to control group normal diet (Teklad 2014S, ENVIGO), but with no added B12 and with 5% Pectin (Tekland custom diet TD.170206, ENVIGO)

This tightly regulated process, influenced by substrate availability, oxygen tension, and cellular energy demand, is crucial for cells with high energy requirements, such as cardiac myocytes, where mitochondria occupy 30% of the cell volume, and neurons, where they are dynamically distributed to synapses

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Regrettably, the majority of the infected population remains unaware of their condition [2]

age-related muscle loss, called sarcopenia, tends to begin around 30 years old

doi: 10.1016/S0140-6736(20)32511-3 [DOI] [PubMed] [Google Scholar]