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APX differs from other peroxidases in its dependency on ASC as the source of reducing power and becomes unstable in its absence (Shigeoka et al., Arabidopsis has 9 APX genes (AtAPX1-AtAPX6, sAPX, tAPX, lAPX) and Oryza sativa has 8 isozymes ( Os APX1- Os APX8), having two APX each in cytosol, peroxisome, chloroplast and mitochondria (Table 1)

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On the other hand, a low ROS state shows an OXPHOS-dominated M2 metabolic mode, featured by efficient ETC and reduced ROS production, which is conducive to the maintenance of M2 polarization and facilitates anti-inflammatory and repair functions (90)

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