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Toxic molecules have slightly higher HBA and number of rotatable bonds, across all quartiles

However, upon depositing in the lungs, these drugs are at risk of undergoing clearance, degradation via metabolism and systemic absorption (Labiris and Dolovich 2003)

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[DOI] [PubMed] [Google Scholar] 73.Melenovsky V., Petrak J., Mracek T., Benes J., Borlaug B.A., Nuskova H., Pluhacek T., Spatenka J., Kovalcikova J., Drahota Z., et al

Lysosomes and peroxisomes also contribute to ferroptosis 58