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Enforced PGC-1 expression promotes CD8 T cell fitness, memory formation and antitumor immunity

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The enzyme glutathione reductase (GR) uses electrons derived from the pentose phosphate pathway to reduce GSSG back into two functional, active GSH molecules, restoring the cellular defense system

10.1073/pnas.1809045115 [DOI] [PMC free article] [PubMed] [Google Scholar] 32.Killilea DW, Ames BN (2008) Magnesium deficiency accelerates cellular senescence in cultured human fibroblasts
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Potential implications of polyphenols on aging considering oxidative stress, inflammation, autophagy, and gut microbiota