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Most patients notice appetite suppression the same day within a few hours of the first dose

95% CI 1.08-1.30) and more often female (aOR = 2.27

However, B12 shots and weight loss are linked in a more indirect way

Some foods like cereal have B-12 added to them
Your provider will customize your schedule

With semaglutide-delayed gastric emptying, this window may need to be even longer, up to 5 hours for some people
