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There is still much work to be done in fully elucidating the changes in energy metabolism signals and their role in heart failure, advancing the development of relevant metabolic therapeutic drugs

Cheng N, Rho JM, Masino SA

Nutraceuticals-based therapeutic approach: recent advances to combat pathogenesis of Alzheimers disease

Thus, cystine starvation induces a stress signal of amino acid limitation through GCN2-eIF2-ATF4 branch in the ISR but not ER stress in HepG2 cells

SAMe is the universal methyl donor necessary for producing the myelin sheaththe protective fatty layer that insulates our nerves and ensures rapid, efficient electrical impulse conduction

doi: 10.1016/j.molp.2020.02.005 123 ZhengJ.FangC.RuL.SunN.LiuY.HuangY.et al