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However, considering the ongoing emergence of resistance and the unclear outlook of existing treatments, undertaking these measures is justified
Substantiation of the hypothesis of BT as a mechanism of sepsis in humans is difficult to demonstrate once trauma or burns have occurred, or when patients are septic, have disrupted circulation to the intestine, or have a damaged intestinal epithelial surface itself

[7] Schneider-Helmert D, Gnirss F, Monnier M, Schenker J, Schoenenberger GA

A Systematic Framework for Understanding the Microbiome in Human Health and Disease: From Basic Principles to Clinical Translation

These are significant gaps

Ethics statement Ethical review and approval was not required for the animal study because Commercially cultured and model fish
