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10.1152/jn.2001.86.5.2312 20 Bunketorp-KallL.Lundgren-NilssonA.SamuelssonH.PeknyT.BlomveK.PeknaM.et al

Given the high and time-consuming costs of developing such a model, as well as the lack of intensive care experience in large animal research, efforts to develop a large-size animal model of ALI/ARDS are still discouraged

Biomarker discoveryincluding epigenetic regulators and microbiome-derived signalsmay enable earlier diagnosis and personalization

The rationale behind the administration of l-ARG as a suitable treatment for vasculogenic ED relies on the matter of fact that l-ARG is an important donor of NO, which is a prominent molecular mediator of the penile erectile process, for the ability to induce cavernous smooth muscle relaxation, and particularly to contribute to the cavernous arteries performance and cavernous blood flow, crucial for penis erection [4, 7]

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