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The key advantages of therapeutic peptides include their high potency, selectivity, minimum side effects, specificity for their target receptors, minimal drug-drug interactions, and reduced immunogenicity [1]

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However, our deepening understanding of the contribution of Fc-dependent effector functions to the protection mediated by vaccines and monoclonal antibodies warrants the development and validation of standardized assays to account for these functions and to assess their contribution to immunity and their possible use as correlates of protection (Box 2)

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