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Curcumin has also been found to counteract the carcinogenic effects of tobacco condensates (492)

PMC 3516448

doi: 10.1371/journal.pone.0098835 223 EguchiJKongXTentaMWangXKangSRosenED

Building on these observations, we demonstrate that co-targeting GLUT1 and GSH metabolism induced a synthetic lethal interaction in glucose deprivation-sensitive glioblastoma and sarcoma cell lines

Sulforaphane (SFN) is produced by the hydrolysis of glucoraphanin after intake of cruciferous vegetables such as broccoli, cabbages, kale, Brussels sprouts, radish, and mustard

Of note, calculation of G values on the basis of estimated intracellular concentrations would result in negative G values for GSH-mediated reduction steps (first and last steps)