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Shikonin induces glioma cell necroptosis in vitro by ROS overproduction and promoting RIP1/RIP3 necrosome formation
In human cancer cell studies or in vivo models (hepatocellular, breast, lung, and others), OA and its derivatives significantly inhibited the carcinogenesis, reduced the growth and proliferation of cancer cells, induced their apoptosis, showed cytotoxic effects, or inhibited angiogenesis, invasion, and metastasis [279,280,281,282,283,284,285,286,287,288,289,290,291,292]
[88] assessed the effect of a diet supplemented with ALA on hippocampus-dependent memory of aged Tg2576 mice with AD
Robin LM, Oliveira da Cruz J, Langlais VC, Martin-Fernandez M, Metna-Laurent M, Busquets-Garcia A, et al
Med 381, 455464 [DOI] [PubMed] [Google Scholar] 111.Harrison C (2019) First gene therapy for -thalassemia approved
10.1016/s0076-6879(99)99026-2 14 AtamnaH.CheungI.AmesB
