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In addition, the upregulation of chemokines in this phase can guide the migration of transplanted cells to the injured area, such as monocyte chemotactic protein-1 (MCP-1) and stromal cell-derived factor-1 (SDF-1) (Lee et al., 2015)

Kreuz et al, 1996

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IL-10 is especially recognized as a preeminent anti-inflammatory and multifunctional cytokine within the immune framework (249)

DISCUSSION The goal of this study was to develop an AngIV-derived molecule that retained the procognitive/antidementia activity of AngIV and Nle 1 -AngIV but possessed improved pharmacokinetic properties, thus allowing it to penetrate the BBB in sufficient quantities to reach therapeutic levels in the brain
